10:00-10:30

Coffee break

Session I

Chair: Franziska Hentzschel

10:30-10:45

Gabriele Pradel

Welcome speech

10:45-11:30

Isabelle Tardieux (Keynote)

Revisiting the minimal force requirements behind Toxoplasma high-speed gliding motility

11:30-11:45

Elena Jimenez Ruiz

The novel conoidal methyltransferase PCKMT is responsible for the initiation of motility in concert with other conoidal proteins in Toxoplasma gondii

11:45-12:00

Martin Blume

Targeting the egress of Toxoplasma gondii bradyzoites

12:00-13:30

Lunch

Session II

Chair: Alfonso Felipe-López

14:15-14:30

Jonathan Neuber

Characterization of the role of Legionella pneumophila phospholipases during vacuolar egress

14:30-14:45

Christine Lemke

Using transposon-directed insertion site sequencing (TraDIS) to identify bacterial factors essential for the egress of Salmonella Typhimurium from the neonate intestinal epithelial cell

14:45-15:00

Joel Selkrig

Dissecting the role of cholesterol trafficking in pathogen-containing vacuole stability

15:00-15:15

Ulrich Dobrindt

Let's get out: Characterization of host and bacterial factors affecting the exit of uropathogenic Escherichia coli from intracellular bacterial communities in bladder epithelial cells

15:15-15:45

Coffee break

Session III

Chair: Lydia Kasper

15:45-16:30

Michel Desjardins (Keynote)

A link between infection and Parkinson's disease

16:30-16:45

Johannes Sonnberger

Escape of the fungal pathogen Candida albicans from macrophages is mediated by filamentation and cytolytic toxin production

16:45-17:00

Theresa Lange

Strategies of Candida glabrata to persist and escape from macrophages

17:00-18:00

Poster Session I

18:00-20:00

Dinner

Impulse Lectures

Chair: Gabriele Pradel

20:00-20:30

Makoah Nigel Aminake

Chikungunya Fever in Africa

20:30-21:00

Anton Aebischer

Ins and Outs of (protozoan) parasite research at a Public Health Institute

Session IV

Chair: Elena Jimenez-Ruiz

08:30-08:45

Katherina Psathaki

Platform 1: The iBiOs imaging platform: State-of-the-art 2D and 3D CLEM for SPP 2225

08:45-09:00

Stefan Tenzer

Platform 2: High sensitivity proteomics to characterize molecular mechanisms of pathogen egress

09:00-09:15

Moritz Jaedtka

Cell death dependency of Leishmania exit from infected macrophages

09:15-09:30

Iris Baars

Intracellular Leishmania major parasites drive host cell death and cell-to-cell transfer depending on the rate of pathogen proliferation

09:30-09:45

Andreas Müller

L. major hijacks hypoinflammatory monocytes to perpetuate infection in an interleukin-7 dependent feedback loop

09:45-10:15

Coffee break

Session V

Chair: Martin Blume

10:15-11:00

Maximiliano Gutierrez (Keynote)

Mycobacterium tuberculosis infection of macrophages in time and space

11:00-11:15

Thomas Gutsmann

Microbes and humans: A battle between membranes and pores

11:15-11:30

Christian Nehls

Membrane interaction of virulence factors of intracellular pathogens studied with time-resolved and high-resolution atomic force microscopy

11:30-11:45

Sylvana Hüttel

Prison break - Deficiency in the mycobacterial acyl-CoA synthetase FACL6 exacerbates membrane damage and phagosome escape of M. marinum in Dictyostelium discoideum

11:45-12:00

Monika Rangole

Inside out - The role of mycobacterial ESX secretion systems in phagosome escape

12:00-13:30

Lunch

Session VI

Chair: Joachim Matz

13:30-14:15

Oliver Billker (Keynote)

Sexual reproduction in malaria parasites - Insights from systematic genetic screens in Plasmodium berghei

14:15-14:30

Juliane Saßmannshausen

A proteomic view on the egress-related vesicles of malaria gametocytes

14:30-14:45

Franziska Hentzschel

ARC40 is essential for the segregation of DNA during the exit of Plasmodium male gametes

14:45-15:00

Sherihan Musa

The P. falciparum histone methyltransferase SET2 during gametocytogenesis

15:00-15:30

Coffee break

Session VII

Chair: Joel Selkrig

15:30-16:15

Jost Enninga (Keynote)

Imag(in)ing the intracellular niche formation of bacterial pathogens

16:15-16:30

Xiao Liu

LukAB is essential for Staphylococcus aureus exit from within macrophages

16:30-16:45

Anja Lührmann/Alfonso Felipe-López

Egress mechanisms of Coxiella burnetii

16:45-17:00

Jana Scholz

The non-lytic exit pathway of Chlamydia psittaci

17:00-17:15

Vera Kozjak-Pavlovic

The release of Simkania negevensis from infected cells depends on the modulation of host cell death and lysis

17:15-18:30

Poster Session II

18:00-19:00

Parallel: PI Meeting

18:30-20:30

Dinner

Panel Discussion

“Good Scientific Practice – Theory and Reality”

Chair: René Lesnik

20:30-21:30

Sascha Brunke

Deputy Head of the Department for Microbial Pathogenicity Mechanisms, HKI Jena

Elizabeth Hartland

Director and CEO of Hudson Institute of Medical Research in Melbourne and Head of the Department of Molecular and Translational Sciences, Monash University

Elke Müller

Head of the Department for Research, RWTH Aachen University

Friedrich Frischknecht

Deputy Head of Parasitology Unit, University Hospital Heidelberg; Editor-in-Chief at Molecular Microbiology

Session VIII

Chair: Xiao Liu

08:15-09:00

Elizabeth Hartland (Keynote)

Bacterial effector proteins as tools for understanding host-pathogen interactions

09:00-09:15

Tobias Dallenga

Identification of a PAD4-independent form of NETosis upon M. tuberculosis infection as both, novel pathogen escape mechanism and host-directed therapy target to prevent mycobacterial proliferation

09:15-09:30

Sebastian Theobald/Jan Rybniker

Programmed cell death in Mycobacterium tuberculosis-infected phagozytes as pathogen EXIT strategy

09:30-09:45

Philipp Henneke

Macrophage ontogeny and programming at site define mycobacterial persistance and immunity in soft tissue infections

09:45-10:15

Coffee break

Session IX

Chair: Sandra Bennink

10:15-10:30

Joachim Matz

The role of Plasmodium V-ATPase in vacuolar physiology and antimalarial drug uptake

10:30-10:45

Kai Matuschewski

Expansion of a malarial parasite antigen family in the mammalian host can be explained by synthetic viability of a lethal Plasmodium berghei cysteine protease defect

10:45-11:00

Mattea Scheiner

Plasmodium egress from the liver infection stage

11:00-11:15

Korbinian Niedermüller

Probing into the molecular pathway leading to Plasmodium falciparum egress from the red blood cell

11:15-11:30

Gabriele Pradel

Closing ceremony

11:30-12:30

Lunch

12:30-15:30

Guided tour through the Augustusburg Castle

15:30-16:00

Coffee break

16:00-19:00

Workshop “Kommunikationsstrategien“

Marion Knaths, sheboss

19:00-21:00

Dinner

21:00-22:00

Group Discussion: Academic Careers: Which way to go?

10:00-17:00

PhD Fun Day - Phantasialand