Das Programm


Das finale Programm:

Thursday, May 05, 2022:

Venue: Ford-Hall, 6th floor of the RWTH SuperC-building, Templergraben 57, 52062 Aachen

11:00 – 11:20 Gabriele Pradel (RWTH Aachen University)


Session 1: The technical platform

Chair: Gabriele Pradel (RWTH Aachen University)

11:20 – 11:40 Julia Maria Post (University Medical Center Mainz – platform 1, Bindila lab)

High resolution mass spectrometry-based strategies for lipid biomarker discovery and quantitative lipidomics from pathogens

11:40 – 12:00 Katherina Psathaki (Center of Cellular Nanoanalytics Osnabrück – platform 2)

The iBiOs imaging platform: State-of-the-art 2D and 3D CLEM for SPP 2225

LUNCH BREAK 12:0013:00

including poster viewing

Session 2: EXIT by: Vacuolar escape and membrane-dependent exit

Chairs: Anja Lührmann (University Hospital Erlangen) & Sujaan Das (Ludwig-Maximilians-University Munich)

13:00 – 13:20 Caroline Barisch (University of Osnabrück – Barisch lab)

How vacuolar and cytosolic mycobacteria exploit host lipid droplets and components of the lipid trafficking machinery

13:20 – 13:40 Sylvana Victoria Hüttel (University of Osnabrück – Barisch lab)

How a perturbation in fatty acid homeostasis affects mycobacterial phagosome escape

13:40 – 14:00 Monika Rangole (Research Center Borstel – Gutsmann lab)

Inside out - The role of mycobacterial ESX secretion systems in phagosome escape

14:00 – 14:20 Monica Hagedorn (Jacobs University Bremen)

The ejectosome facilitates non-lytic egress of Mycobacterium marinum from the amoeba Dictyostelium discoideum

14:20 – 14:40 Matthea Scheiner (Humboldt University Berlin – Ingmundson Lab)

Plasmodium egress from the liver infection stage

COFFEE BREAK 14:40 – 15:00

15:00 – 15:20 Sabrina Wamp (Robert Koch-Institute Wernigerode – Flieger lab)

The Legionella pneumophila GDSL hydrolases PlaA, PlaC and PlaD and their role in host cell infection and exit

15:20 – 15:40 Jonathan Neuber (Robert Koch-Institute Wernigerode – Flieger lab)

Function of Legionella pneumophila phospholipases in vacuole and host egress

15:40 – 16:00 Christine Nieves Hernandez (Freie Universität Berlin – Fulde lab)

Using population dynamics and transposon-directed insertion site sequencing (TraDIS) to identify bacterial factors essential for the egress from the neonate epithelial cell

16:00 – 16:20 Nour Diab (RWTH Aachen University – Hornef lab)

Bacterial and host factors governing enterocyte egress of Salmonella


Venue: Lecture Hall H01, CARL building of RWTH Aachen University, Claßenstraße 11, 52072 Aachen

17:00 – 18:00 Melanie Brinkmann (Technical University Braunschweig)

Die Corona-Pandemie: Fluch oder Segen? Lehren aus 2 Jahren Pandemie

Followed by: Meet the speaker

SPP 2225 DINNER 19:30 – 22:00

Venue: Karl`s Wirtshaus, Markt 17, 52062 Aachen

Friday, May 06, 2022:

Venue: Ford-Hall, 6th floor of the RWTH SuperC-building, Templergraben 57, 52062 Aachen

Session 3: EXIT by: Programmed cell death

Chairs: Alyssa Ingmundson (Humboldt University Berlin) & Paul Burda (Centre for Structural Systems Biology Hamburg)

09:00 – 09:20 Lydia Kasper & Theresa Rothe (Hans-Knöll-Institute Jena – Brunke/Hube lab)

Diverse strategies of Candida albicans and Candida glabrata to exit from macrophages

09:20 – 09:40 Florens Lohmann (University Medical Center Freiburg – Henneke lab)

Mycobacteria sequentially interact with macrophage subsets in skin infection

09:40 – 10:00 Jana Scholz (Robert Koch-Institute Berlin – Heuer lab)

Deciphering the role of sphingolipids in bacterial egress

10:00 – 10:20 Xiao Liu (University Tübingen – Weber/Wolz lab)

Regulation of NLRP3 inflammasome by Staphylococcus aureus within macrophages

10:20 – 10:40 Mohamed Balboul (University Hospital Erlangen – Lührmann lab)

Egress mechanisms of Coxiella burnetii

10:40 – 11:00 Moritz Jaedtka (Paul Ehrlich Institute Langen – van Zandbergen/Müller lab)

Cell death dependency of Leishmania exit from infected macrophages

COFFEE BREAK 11:00 – 11:20

Session 4: EXIT by: Host cell lysis

Chairs: Monica Hagedorn (Jacobs University Bremen) & Ger van Zandbergen (Paul Ehrlich Institute Langen)

11:20 – 11:40 Janessa Grech (Ludwig-Maximilians-University Munich – Meißner/Das lab)

Two essential apical proteins identified by a splitCas9 phenotypic screen are important at different egress steps in Toxoplasma gondii

11:40 – 12:00 Kim Chi Vo (Humboldt University Berlin – Gupta lab)

Cyclic nucleotide phosphodiesterases in Toxoplasma gondii

12:00 – 12:20 Buyan He (University Hospital Heidelberg – Frischknecht lab)

Understanding MTRAP-mediated formation and egress of Plasmodium by 3D electron microscopy

12:20 – 12:40 Korbinian Niedermüller (CSSB Hamburg – Gilberger/Burda lab )

Identification and characterization of novel factors mediating Plasmodium falciparum egress from the red blood cell

12:40 – 13:00 Juliane Saßmannshausen (RWTH Aachen University – Pradel lab)

A proteomic view on the egress-related vesicles of malaria gametocytes

LUNCH BREAK 13:00 – 14:00

including poster viewing

14:00 – 15:00 General round table discussion of PIs

Starting 14:00 Meeting of the PhD students