The programme
Finale Programme:
Thursday, May 05, 2022:
Venue: Ford-Hall, 6th floor of the RWTH SuperC-building, Templergraben 57, 52062 Aachen
11:00 – 11:20 Gabriele Pradel (RWTH Aachen University)
Welcome
Session 1: The technical platform
Chair: Gabriele Pradel (RWTH Aachen University)
11:20 – 11:40 Julia Maria Post (University Medical Center Mainz – platform 1, Bindila lab)
High resolution mass spectrometry-based strategies for lipid biomarker discovery and quantitative lipidomics from pathogens
11:40 – 12:00 Katherina Psathaki (Center of Cellular Nanoanalytics Osnabrück – platform 2)
The iBiOs imaging platform: State-of-the-art 2D and 3D CLEM for SPP 2225
LUNCH BREAK 12:00 – 13:00
including poster viewing
Session 2: EXIT by: Vacuolar escape and membrane-dependent exit
Chairs: Anja Lührmann (University Hospital Erlangen) & Sujaan Das (Ludwig-Maximilians-University Munich)
13:00 – 13:20 Caroline Barisch (University of Osnabrück – Barisch lab)
How vacuolar and cytosolic mycobacteria exploit host lipid droplets and components of the lipid trafficking machinery
13:20 – 13:40 Sylvana Victoria Hüttel (University of Osnabrück – Barisch lab)
How a perturbation in fatty acid homeostasis affects mycobacterial phagosome escape
13:40 – 14:00 Monika Rangole (Research Center Borstel – Gutsmann lab)
Inside out - The role of mycobacterial ESX secretion systems in phagosome escape
14:00 – 14:20 Monica Hagedorn (Jacobs University Bremen)
The ejectosome facilitates non-lytic egress of Mycobacterium marinum from the amoeba Dictyostelium discoideum
14:20 – 14:40 Matthea Scheiner (Humboldt University Berlin – Ingmundson Lab)
Plasmodium egress from the liver infection stage
COFFEE BREAK 14:40 – 15:00
15:00 – 15:20 Sabrina Wamp (Robert Koch-Institute Wernigerode – Flieger lab)
The Legionella pneumophila GDSL hydrolases PlaA, PlaC and PlaD and their role in host cell infection and exit
15:20 – 15:40 Jonathan Neuber (Robert Koch-Institute Wernigerode – Flieger lab)
Function of Legionella pneumophila phospholipases in vacuole and host egress
15:40 – 16:00 Christine Nieves Hernandez (Freie Universität Berlin – Fulde lab)
Using population dynamics and transposon-directed insertion site sequencing (TraDIS) to identify bacterial factors essential for the egress from the neonate epithelial cell
16:00 – 16:20 Nour Diab (RWTH Aachen University – Hornef lab)
Bacterial and host factors governing enterocyte egress of Salmonella
KEYNOTE LECTURE
Venue: Lecture Hall H01, CARL building of RWTH Aachen University, Claßenstraße 11, 52072 Aachen
17:00 – 18:00 Melanie Brinkmann (Technical University Braunschweig)
Die Corona-Pandemie: Fluch oder Segen? Lehren aus 2 Jahren Pandemie
Followed by: Meet the speaker
SPP 2225 DINNER 19:30 – 22:00
Venue: Karl`s Wirtshaus, Markt 17, 52062 Aachen
Friday, May 06, 2022:
Venue: Ford-Hall, 6th floor of the RWTH SuperC-building, Templergraben 57, 52062 Aachen
Session 3: EXIT by: Programmed cell death
Chairs: Alyssa Ingmundson (Humboldt University Berlin) & Paul Burda (Centre for Structural Systems Biology Hamburg)
09:00 – 09:20 Lydia Kasper & Theresa Rothe (Hans-Knöll-Institute Jena – Brunke/Hube lab)
Diverse strategies of Candida albicans and Candida glabrata to exit from macrophages
09:20 – 09:40 Florens Lohmann (University Medical Center Freiburg – Henneke lab)
Mycobacteria sequentially interact with macrophage subsets in skin infection
09:40 – 10:00 Jana Scholz (Robert Koch-Institute Berlin – Heuer lab)
Deciphering the role of sphingolipids in bacterial egress
10:00 – 10:20 Xiao Liu (University Tübingen – Weber/Wolz lab)
Regulation of NLRP3 inflammasome by Staphylococcus aureus within macrophages
10:20 – 10:40 Mohamed Balboul (University Hospital Erlangen – Lührmann lab)
Egress mechanisms of Coxiella burnetii
10:40 – 11:00 Moritz Jaedtka (Paul Ehrlich Institute Langen – van Zandbergen/Müller lab)
Cell death dependency of Leishmania exit from infected macrophages
COFFEE BREAK 11:00 – 11:20
Session 4: EXIT by: Host cell lysis
Chairs: Monica Hagedorn (Jacobs University Bremen) & Ger van Zandbergen (Paul Ehrlich Institute Langen)
11:20 – 11:40 Janessa Grech (Ludwig-Maximilians-University Munich – Meißner/Das lab)
Two essential apical proteins identified by a splitCas9 phenotypic screen are important at different egress steps in Toxoplasma gondii
11:40 – 12:00 Kim Chi Vo (Humboldt University Berlin – Gupta lab)
Cyclic nucleotide phosphodiesterases in Toxoplasma gondii
12:00 – 12:20 Buyan He (University Hospital Heidelberg – Frischknecht lab)
Understanding MTRAP-mediated formation and egress of Plasmodium by 3D electron microscopy
12:20 – 12:40 Korbinian Niedermüller (CSSB Hamburg – Gilberger/Burda lab )
Identification and characterization of novel factors mediating Plasmodium falciparum egress from the red blood cell
12:40 – 13:00 Juliane Saßmannshausen (RWTH Aachen University – Pradel lab)
A proteomic view on the egress-related vesicles of malaria gametocytes
LUNCH BREAK 13:00 – 14:00
including poster viewing
14:00 – 15:00 General round table discussion of PIs
Starting 14:00 Meeting of the PhD students