CV Laura Bindila
Laura Bindila received her PhD in Physics in 2006 with Summa cum Laude from Babes-Bolyai University, Clubj Napoca, Romania. She carried out her PhD project and postdoctoral phase at the Institute for Medical Physics and Biophysics Münster, where she focused on development and application hyphenated mass spectrometry methods for glycolipids analysis. She then took a scientist position at the Clinical Proteomics Laboratory at the Center for Public Research in Luxembourg where her she focused on glycoproteomics.
Since 2012 she is heading the Lipidomics research group and the Lipidomics Core Facility which she established in 2015 at the Institute of Physiological Chemistry, University Medical Center of Mainz. Her research is focused on the lipid signalling and lipidome dynamic with diseases in particular in cardiovascular, infections
and neurological diseases. Since 2020 she is PI at the Mainz Research Center Mass Spectrometry (DIASyM). She also serves as PI at the TransMed program and DZHK. Since 2020 she acts as Editor for Rapid Communication in Mass Spectrometry. Since 2006 she is member of the organizing committee of and lecturer at the School for Mass Spectrometry in Biotechnology and Medicine.
Selected Publications:
- Meyer zu Reckendorf S, Brand C, Pedro MT, Hegler J, Schilling CS, Lerner R, Bindila L, Antoniadis G, and Knöll B (2020) Lipid metabolism adaptations are reduced in human compared to murine Schwann cells following injury. Nat Commun 11:2123.
- Collu R, Post JM, Scherma M, Giunti E, Fratta W, Lutz B, Fadda P, and Bindila L (2020) Altered brain levels of arachidonic acid-derived inflammatory eicosanoids in a rodent model of anorexia nervosa . Biochim Biophys Acta - Mol Cell Biol Lipids 1865:158578.
- Lerner R, Cuadrado DP, Post JM, Lutz B, and Bindila L (2019) Broad lipidomic and transcriptional changes of prophylactic PEA administration in control mice. Front Neurosci 13:527-
- Heide EC, Bindila L, Post JM, Malzahn D, Lutz B, Seele J, Nau R, and Ribes S (2018) Prophylactic palmitoylethanolamide prolongs survival and decreases detrimental inflammation in aged mice with bacterial meningitis. Front Immunol 9:2671.
- Lerner R, Post JM, Ellis SR, Naomi Vos DR, Heeren RMA, Lutz B, and Bindila L (2018) Simultaneous lipidomic and transcriptomic profiling in mouse brain punches of acute epileptic seizure model compared to controls. J Lipid Res 59:283–297.
- Post JM, Loch S, Lerner R, Remmers F, Lomazzo E, Lutz B, and Bindila L (2018) Antiepileptogenic effect of subchronic palmitoylethanolamide treatment in a mouse model of acute epilepsy. Front Mol Neurosci 11:1–17.
- Lerner R, Post J, Loch S, Lutz B, and Bindila L (2017) Targeting brain and peripheral plasticity of the lipidome in acute kainic acid-induced epileptic seizures in mice via quantitative mass spectrometry. Biochim Biophys Acta - Mol Cell Biol Lipids 1862:255–267.
- Scott AJ, Post JM, Lerner R, Ellis SR, Lieberman J, Shirey KA, Heeren RMA, Bindila L, and Ernst RK (2017) Host-based lipid inflammation drives pathogenesis in Francisella infection. Proc Natl Acad Sci USA 114:12596–12601.
- Bindila L, and Peter-Katalinic J (2009) Chip-mass spectrometry for glycomic studies. Mass Spectrom Rev 28:223–253.
- Kirsch S, Müthing J, Peter-Katalinić J, and Bindila L (2009) On-line nano-HPLC/ESI QTOF MS monitoring of α2-3 and α2-6 sialylation in granulocyte glycosphingolipidome. Biol Chem 390:657–672.