CV Sujaan Das

 

Sujaan Das received his PhD in 2014 from the MRC National Institute for Medical Research (now the Francis Crick Institute, London, UK), where he worked on developing novel genetic tools to study essential proteins in the malaria parasite, Plasmodium falciparum. He held the prestigious ERC-FP7 Network of Excellence funded EVIMalaR fellowship during his PhD. Thereafter he worked as a Research Associate at the Wellcome Centre for Integrated Parasitology at the University for Glasgow, Scotland.

In 2019 Sujaan Das received the Marie Skłodowska-Curie COFUND – LMU Incoming Fellowship to independently establish his research at the Ludwig Maximilian University of Munich, within the Chair for Experimental Parasitology. He focuses on the unique molecular mechanisms of the actin cytoskeleton in P. falciparum, with a dual goal of understanding basic biology together with development of novel therapeutics.

Selected Publications:

  1. Watzlowik MT, Das S, Meissner M, Längst G. (2021) Peculiarities of Plasmodium falciparum Gene Regulation and Chromatin Structure. Int J Mol Sci 22:5168.
  2. Stortz JF, Del Rosario M, Singer M, Wilkes JM, Meissner M, Das S (2019) Formin-2 drives polymerisation of actin filaments enabling segregation of apicoplasts and cytokinesis in Plasmodium falciparum . Elife 8:e49030.
  3. Del Rosario M, Periz J, Pavlou G, Lyth O, Latorre-Barragan F, Das S, Pall GS, Stortz JF, Lemgruber L, Whitelaw JA, Baum J, Tardieux I, Meissner M (2019) Apicomplexan F-actin is required for efficient nuclear entry during host cell invasion. EMBO Rep 20:e48896.
  4. Das S, Lemgruber L, Tay CL, Baum J, Meissner M (2017) Multiple essential functions of Plasmodium falciparum actin-1 during malaria blood-stage development. BMC Biol 15:70.
  5. Jones ML, Das S, Belda H, Collins CR, Blackman MJ, Treeck M (2016) A versatile strategy for rapid conditional genome engineering using loxP sites in a small synthetic intron in Plasmodium falciparum. Sci Rep 6:21800.
  6. Das S, Hertrich N, Perrin AJ, Withers-Martinez C, Collins CR, Jones ML, Watermeyer JM, Fobes ET, Martin SR, Saibil HR, Wright GJ, Treeck M, Epp C, Blackman MJ (2015) Processing of Plasmodium falciparum Merozoite Surface Protein MSP1 Activates a Spectrin-Binding Function Enabling Parasite Egress from RBCs. Cell Host Microbe 18:433-444.
  7. Pieperhoff MS, Pall GS, Jiménez-Ruiz E, Das S, Melatti C, Gow M, Wong EH, Heng J, Müller S, Blackman MJ, Meissner M (2015) Conditional U1 Gene Silencing in Toxoplasma gondii. PLoS One 10:e0130356.
  8. Collins CR, Das S, Wong EH, Andenmatten N, Stallmach R, Hackett F, Herman JP, Müller S, Meissner M, Blackman MJ (2013) Robust inducible Cre recombinase activity in the human malaria parasite Plasmodium falciparum enables efficient gene deletion within a single asexual erythrocytic growth cycle. Mol Microbiol 88:687-701.